Factor V Leiden Mutation, DNA Analysis

Factor V Leiden is the most common inherited clotting disorder. This one-time DNA test checks for a variant in the F5 gene that makes blood more likely to form abnormal clots (thrombophilia) — useful context for prevention and for decisions around hormones, surgery, or pregnancy.

What it tells you

• Whether you carry one copy (heterozygous) — a moderate increase in clot risk
• Or two copies (homozygous) — a substantially higher risk
• Risk context for DVT, pulmonary embolism, and related events

Who should consider it

• A personal or family history of unexplained blood clots
• Recurrent pregnancy loss
• Anyone weighing hormone therapy or oral contraceptives

About this test

Genetic — your result doesn't change, so it's a one-time test. No fasting required.