Factor II Activity (Clotting)

Factor II (prothrombin) is a protein essential for blood clot formation. When a blood vessel is injured, Factor II is converted into thrombin, which triggers the clotting cascade that stops bleeding. This test measures the functional activity level of Factor II in the blood. Low Factor II activity may indicate a clotting disorder, liver disease, vitamin K deficiency, or the effects of anticoagulant therapy. Elevated activity may be associated with an increased risk of thrombotic events. Factor II Activity testing is often used alongside other coagulation studies to evaluate unexplained bleeding, clotting disorders, or abnormal PT/INR results.

Diagnostic Blood Test:

• Factor II Activity