APOE Genotyping (Alzheimer's Risk)

The APOE gene provides instructions for making apolipoprotein E, a protein involved in cholesterol transport and fat metabolism in the brain. Certain variants of this gene — particularly the APOE ε4 allele — are the strongest known genetic risk factors for late-onset Alzheimer's disease. Carrying one copy of ε4 increases risk moderately, while two copies increase it substantially. The APOE ε2 variant, by contrast, is associated with a reduced risk. This one-time genetic test identifies your APOE genotype, providing actionable insight for those focused on cognitive longevity, neuroprotection strategies, and cardiovascular risk management.